Searchable abstracts of presentations at key conferences in endocrinology

ea0050oc4.4 | Adrenal and Steroids | SFEBES2017

The role of “stress” in aldosterone-mediated hypertension: circumstantial evidence from the “stress subtraction” experiment of adrenal vein sampling

Kline Gregory , Darras Pol , Leung Alexander , Chin Alex , So Benny , Holmes Daniel

Background: Primary aldosteronism (PA) accounts for a significant proportion of patients with hypertension. There has been a focus on ACTH in the pathogenesis of aldosterone secretion even with suppressed renin. With the link between psychological stress and cardiovascular disease as well as the association between anxiety and PA, there may be broader neurohormonal “stress” stimuli that modulate aldosterone production in PA patients, beyond the HPA axis. PA patients ...

ea0050oc4.4 | Adrenal and Steroids | SFEBES2017

The role of “stress” in aldosterone-mediated hypertension: circumstantial evidence from the “stress subtraction” experiment of adrenal vein sampling

Kline Gregory , Darras Pol , Leung Alexander , Chin Alex , So Benny , Holmes Daniel

Background: Primary aldosteronism (PA) accounts for a significant proportion of patients with hypertension. There has been a focus on ACTH in the pathogenesis of aldosterone secretion even with suppressed renin. With the link between psychological stress and cardiovascular disease as well as the association between anxiety and PA, there may be broader neurohormonal “stress” stimuli that modulate aldosterone production in PA patients, beyond the HPA axis. PA patients ...